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1

A new opioid designed multiple ligand derived from the μ opioid agonist endomorphin-2 and the δ opioid antagonist pharmacophore Dmt-Tic

Severo Salvadori, Claudio Trapella, Stella Fiorini, Lucia Negri, Roberta Lattanzi, Sharon D. Bryant, Yunden Jinsmaa, Lawrence H. Lazarus, Gianfranco Balboni

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 160 KB

english, 2007

2

Opioid Peptides: Synthesis and Biological Activity of New Endomorphin Analogues

Barbara Biondi, Elisa Giannini, Lucia Negri, Pietro Melchiorri, Roberta Lattanzi, Federica Rosso, Luigi Ciocca, Raniero Rocchi

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

3

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia

Sarnelli, Giovanni, Seguella, Luisa, Pesce, Marcella, Lu, Jie, Gigli, Stefano, Bruzzese, Eugenia, Lattanzi, Roberta, D’Alessandro, Alessandra, Cuomo, Rosario, Steardo, Luca, Esposito, Giuseppe

Journal:

Journal of Neuroinflammation

Year:

2018

Language:

english

File:

PDF, 3.07 MB

english, 2018

4

PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor

Lattanzi, Roberta, Maftei, Daniela, Negri, Lucia, Fusco, Ilaria, Miele, Rossella

Journal:

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

5

Development and initial validation of composite parent- and child-centered disease assessment indices for juvenile idiopathic arthritis

Alessandro Consolaro, Nicolino Ruperto, Angela Pistorio, Bianca Lattanzi, Nicoletta Solari, Roberta Galasso, Silvia Pederzoli, Giulia C. Varnier, Pavla Dolezalova, Maria Alessio, Ruben Burgos-Vargas,

Journal:

Arthritis Care & Research

Year:

2011

Language:

english

File:

PDF, 141 KB

english, 2011

6

Antinuclear antibody–positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis

Angelo Ravelli, Giulia C. Varnier, Sheila Oliveira, Esteban Castell, Olga Arguedas, Alessandra Magnani, Angela Pistorio, Nicolino Ruperto, Silvia Magni-Manzoni, Roberta Galasso, Bianca Lattanzi, Sara

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 115 KB

english, 2011

7

Up-regulation of nuclear PLCβ1 in myogenic differentiation

Irene Faenza, Alberto Bavelloni, Roberta Fiume, Giovanna Lattanzi, Nadir M. Maraldi, R. Stewart. Gilmour, Alberto M. Martelli, Pann-Ghill Suh, Anna Maria Billi, Lucio Cocco

Journal:

Journal of Cellular Physiology

Year:

2003

Language:

english

File:

PDF, 209 KB

english, 2003

8

Conformationally constrained opioid ligands: The Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold

Steven Ballet, Debby Feytens, Rien De Wachter, Magali De Vlaeminck, Ewa D. Marczak, Severo Salvadori, Chris de Graaf, Didier Rognan, Lucia Negri, Roberta Lattanzi, Lawrence H. Lazarus, Dirk Tourwé, Gi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 656 KB

english, 2009

9

Novel glycosylated [Lys7]-dermorphin analogues: synthesis, biological activity and conformational investigations

Laura Biondi, Fernando Filira, Elisa Giannini, Marina Gobbo, Roberta Lattanzi, Lucia Negri, Raniero Rocchi

Journal:

Journal of Peptide Science

Year:

2007

Language:

english

File:

PDF, 224 KB

english, 2007

10

Analogues of both Leu- and Met-enkephalin containing a constrained dipeptide isostere prepared from a Baylis-Hillman adduct

Roberta Galeazzi, Gianluca Martelli, Eleonora Marcucci, Mario Orena, Samuele Rinaldi, Roberta Lattanzi, Lucia Negri

Journal:

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

11

Novel Nociceptin Analogues: Synthesis and Biological Activity

Barbara Biondi, Dante Goldin, Elisa Giannini, Roberta Lattanzi, Lucia Negri, Pietro Melchiorri, Luigi Ciocca, Raniero Rocchi

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

12

The prokineticin receptor agonist Bv8 increases GABA release in the periaqueductal grey and modifies RVM cell activities and thermoceptive reflexes in the rat

Vito De Novellis, Lucia Negri, Roberta Lattanzi, Francesca Rossi, Enza Palazzo, Ida Marabese, Elisa Giannini, Daniela Vita, Pietro Melchiorri, Sabatino Maione

Journal:

European Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 405 KB

english, 2007

13

Respiratory and cardiovascular effects of the μ-opioid receptor agonist [Lys7]dermorphin in awake rats

Lucia Negri, Roberta Lattanzi, Fabio Tabacco, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 453 KB

english, 1998

14

Glycodermorphins: opioid peptides with potent and prolonged analgesic activity and enhanced blood-brain barrier penetration

Lucia Negri, Roberta Lattanzi, Fabio Tabacco, Barbara Scolaro, Raniero Rocchi

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 368 KB

english, 1998

15

Effects of antisense oligonucleotides on brain delta-opioid receptor density and on SNC80-induced locomotor stimulation and colonic transit inhibition in rats

Lucia Negri, Maria Broccardo, Roberta Lattanzi, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

16

Nociceptive sensitization by the secretory protein Bv8

Lucia Negri, Roberta Lattanzi, Elisa Giannini, Alessio Metere, Mariantonella Colucci, Donatella Barra, Günther Kreil, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

17

Bv8, the amphibian homologue of the mammalian prokineticins, modulates ingestive behaviour in rats

Lucia Negri, Roberta Lattanzi, Elisa Giannini, Milena De Felice, Antonella Colucci, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

18

Biological activities of Bv8 analogues

Lucia Negri, Roberta Lattanzi, Elisa Giannini, Maria Antonella Colucci, Giuseppina Mignogna, Donatella Barra, Fabio Grohovaz, Franca Codazzi, Alessandra Kaiser, Guenther Kreil, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 200 KB

english, 2005

19

Effects of the intravenous administration of [Lys7]dermorphin on local cerebral glucose utilization in the rat

Francesco E. Pontieri, Roberta Lattanzi, Dario Benincasa, Michele Cavallari, Lucia Negri, Francesco Orzi

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 108 KB

english, 2006

20

The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

Silvia Franchi, Elisa Giannini, Donatella Lattuada, Roberta Lattanzi, Hui Tian, Pietro Melchiorri, Lucia Negri, Alberto E Panerai, Paola Sacerdote

Journal:

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

21

Synthesis and Biological Evaluation of 14-Alkoxymorphinans. 22.1 Influence of the 14-Alkoxy Group and the Substitution in Position 5 in 14-Alkoxymorphinan-6-ones on in Vitro and in Vivo Activities

Lattanzi, Roberta, Spetea, Mariana, Schüllner, Falko, Rief, Silvia B., Krassnig, Roland, Negri, Lucia, Schmidhammer, Helmut

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

22

Bv8/PK2 and prokineticin receptors: a druggable pronociceptive system

Lucia Negri, Roberta Lattanzi

Journal:

Current Opinion in Pharmacology

Year:

2012

Language:

english

File:

PDF, 572 KB

english, 2012

23

Bv8/Prokineticin proteins and their receptors

Lucia Negri, Roberta Lattanzi, Elisa Giannini, Pietro Melchiorri

Journal:

Year:

2007

Language:

english

File:

PDF, 1.37 MB

english, 2007

24

Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding

Rossella Miele, Roberta Lattanzi, Maria Carmela Bonaccorsi di Patti, Alessandro Paiardini, Lucia Negri, Donatella Barra

Journal:

Protein Expression and Purification

Year:

2010

Language:

english

File:

PDF, 299 KB

english, 2010

25

Pharmacology of Amphibian Opiate Peptides

Lucia Negri, Pietro Melchiorri, Roberta Lattanzi

Journal:

Year:

2000

Language:

english

File:

PDF, 88 KB

english, 2000

26

Production of antinociception by peripheral administration of [Lys7]dermorphin, a naturally occurring peptide with high affinity for μ-opioid receptors

Lucia Negri, Roberta Lattanzi, Pietro Melchiorri

Journal:

British Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 2.04 MB

english, 1995

27

Influence of the 14-alkoxy group and the substitution in position 5 inN-methyl-14-alkoxymorphinan-6-ones onin vitroandin vivopharmacological activities

Haddou, Tanila, Lattanzi, Roberta, Negri, Lucia, Schmidhammer, Helmut, Spetea, Mariana

Journal:

BMC Pharmacology and Toxicology

Year:

2012

Language:

english

File:

PDF, 83 KB

english, 2012

28

New 2‘,6‘-Dimethyl- l -tyrosine (Dmt) Opioid Peptidomimetics Based on the Aba-Gly Scaffold. Development of Unique μ-Opioid Receptor Ligands

Ballet, Steven, Salvadori, Severo, Trapella, Claudio, Bryant, Sharon D., Jinsmaa, Yunden, Lazarus, Lawrence H., Negri, Lucia, Giannini, Elisa, Lattanzi, Roberta, Tourwé, Dirk, Balboni, Gianfranco

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

29

A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists

Congiu, Cenzo, Onnis, Valentina, Deplano, Alessandro, Salvadori, Severo, Marconi, Veronica, Maftei, Daniela, Negri, Lucia, Lattanzi, Roberta, Balboni, Gianfranco

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

30

6- N,N -Dimethylamino-2,3-naphthalimide: A New Environment-Sensitive Fluorescent Probe in δ- and μ-Selective Opioid Peptides

Vázquez, M. Eugenio, Blanco, Juan B., Salvadori, Severo, Trapella, Claudio, Argazzi, Roberto, Bryant, Sharon D., Jinsmaa, Yunden, Lazarus, Lawrence H., Negri, Lucia, Giannini, Elisa, Lattanzi, Roberta

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

31

Highly Selective Fluorescent Analogue of the Potent δ-Opioid Receptor Antagonist Dmt-Tic

Balboni, Gianfranco, Salvadori, Severo, Dal Piaz, Alessandro, Bortolotti, Fabrizio, Argazzi, Roberto, Negri, Lucia, Lattanzi, Roberta, Bryant, Sharon D., Jinsmaa, Yunden, Lazarus, Lawrence H.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

32

Dermorphin and Deltorphin Glycosylated Analogues: Synthesis and Antinociceptive Activity after Systemic Administration †

Negri, Lucia, Lattanzi, Roberta, Tabacco, Fabio, Orrù, Luigi, Severini, Cinzia, Scolaro, Barbara, Rocchi, Raniero

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 47 KB

english, 1999

33

Triazine Compounds as Antagonists at Bv8-Prokineticin Receptors

Balboni, Gianfranco, Lazzari, Ilaria, Trapella, Claudio, Negri, Lucia, Lattanzi, Roberta, Giannini, Elisa, Nicotra, Annalisa, Melchiorri, Pietro, Visentin, Sergio, Nuccio, Chiara De, Salvadori, Severo

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 478 KB

english, 2008

34

An important role for prokineticin 2 in autoimmune CNS demyelination

Abou-hamdan, Mhamad, Costanza, Massimo, Fontana, Elena, Musio, Silvia, Di Dario, Marco, Congiu, Cenzo, Onnis, Valentina, Lattanzi, Roberta, Negri, Lucia, Poliani, Pietro Luigi, Farina, Cinthia, Balbon

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

35

Differential Knockdown of δ-Opioid Receptor Subtypes in the Rat Brain by Antisense Oligodeoxynucleotides Targeting mRNA

NEGRI, LUCIA, LATTANZI, ROBERTA, BORSODI, ANNA, TOTH, GEZA, SALVADORI, SEVERO

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1999

Language:

english

File:

PDF, 2.45 MB

english, 1999

36

N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans

Truini, Andrea, Piroso, Serena, Pasquale, Erica, Notartomaso, Serena, Di Stefano, Giulia, Lattanzi, Roberta, Battaglia, Giuseppe, Nicoletti, Ferdinando, Cruccu, Giorgio

Journal:

Year:

2015

Language:

english

File:

PDF, 454 KB

english, 2015

37

Modulators of Pain: Bv8 and Prokineticins

Negri, Lucia, Lattanzi, Roberta, Giannini, Elisa, Melchiorri, Pietro

Journal:

Current Neuropharmacology

Year:

2006

Language:

english

File:

PDF, 309 KB

english, 2006

38

Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy

Roncarati, Roberta, Viviani Anselmi, Chiara, Krawitz, Peter, Lattanzi, Giovanna, von Kodolitsch, Yskert, Perrot, Andreas, di Pasquale, Elisa, Papa, Laura, Portararo, Paola, Columbaro, Marta, Forni, Al

Journal:

European Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

39

Binding of bis-(2-ethylhexyl) phthalate at the surface of hydrozincite nanocrystals: An example of organic molecules absorption onto nanocrystalline minerals

Sanna, Roberta, Medas, Daniela, Podda, Francesca, Meneghini, Carlo, Casu, Mariano, Lattanzi, Pierfranco, Scorciapino, Mariano Andrea, Floris, Costantino, Cannas, Carla, De Giudici, Giovanni

Journal:

Journal of Colloid and Interface Science

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

40

Disease activity accounts for long-term efficacy of IL-1 blockers in pyogenic sterile arthritis pyoderma gangrenosum and severe acne syndrome

Omenetti, Alessia, Carta, Sonia, Caorsi, Roberta, Finetti, Martina, Marotto, Daniela, Lattanzi, Bianca, Jorini, Mauro, Delfino, Laura, Penco, Federica, Picco, Paolo, Buoncompagni, Antonella, Martini,

Journal:

Year:

2016

Language:

english

File:

PDF, 522 KB

english, 2016

41

Prokineticins are neuroprotective in models of cerebral ischemia and ischemic tolerance in vitro

Landucci, Elisa, Lattanzi, Roberta, Gerace, Elisabetta, Scartabelli, Tania, Balboni, Gianfranco, Negri, Lucia, Pellegrini-Giampietro, Domenico E.

Journal:

Neuropharmacology

Year:

2016

Language:

english

File:

PDF, 4.82 MB

english, 2016

42

Synthesis and Pharmacological Evaluation of 18,19-Dehydrobuprenorphine

Schmidhammer, Helmut, Schütz, Johannes, Krassnig, Roland, Wurst, Klaus, Lattanzi, Roberta, Negri, Lucia

Journal:

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

43

ChemInform Abstract: A New Convenient Synthetic Method and Preliminary Pharmacological Characterization of Triazinediones as Prokineticin Receptor Antagonists.

Congiu, Cenzo, Onnis, Valentina, Deplano, Alessandro, Salvadori, Severo, Marconi, Veronica, Maftei, Daniela, Negri, Lucia, Lattanzi, Roberta, Balboni, Gianfranco

Journal:

Year:

2014

File:

PDF, 23 KB

2014

44

Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease

Caioli, Silvia, Severini, Cinzia, Ciotti, Teresa, Florenzano, Fulvio, Pimpinella, Domenico, Petrocchi Passeri, Pamela, Balboni, Gianfranco, Polisca, Patrizio, Lattanzi, Roberta, Nisticò, Robert, Negri

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 3.81 MB

english, 2017

45

A rational approach to elucidate human monoamine oxidase molecular selectivity

Mangiatordi, Giuseppe Felice, Alberga, Domenico, Pisani, Leonardo, Gadaleta, Domenico, Trisciuzzi, Daniela, Farina, Roberta, Carotti, Andrea, Lattanzi, Gianluca, Catto, Marco, Nicolotti, Orazio

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 1.80 MB

english, 2017

46

Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

Severini, Cinzia, Lattanzi, Roberta, Maftei, Daniela, Marconi, Veronica, Ciotti, Maria Teresa, Petrocchi Passeri, Pamela, Florenzano, Fulvio, Del Duca, Ester, Caioli, Silvia, Zona, Cristina, Balboni,

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

47

Seasonal variations of amphipod assemblages in a Posidonia oceanica (Linnaeus) Delile, 1813 meadow from the central Tyrrhenian Sea (Italy)

Camisa, Federica, Abbattista, Chiara, Bellisario, Bruno, Angeletti, Dario, Lattanzi, Loretta, Cimmaruta, Roberta

Journal:

Year:

2017

Language:

english

File:

PDF, 654 KB

english, 2017

48

The multidisciplinary support in preventing alcohol relapse after liver transplantation: A single-center experience

Attilia, Maria Luisa, Lattanzi, Barbara, Ledda, Roberta, Galli, Anna Maria, Farcomeni, Alessio, Rotondo, Claudia, Di Gregorio, Vincenza, Mennini, Gianluca, Poli, Edoardo, Attilia, Fabio, Ginanni Corra

Journal:

Clinical Transplantation

Year:

2018

Language:

english

File:

PDF, 630 KB

english, 2018

49

Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

Lattanzi, Roberta, Maftei, Daniela, Marconi, Veronica, Florenzano, Fulvio, Franchi, Silvia, Borsani, Elisa, Rodella, Luigi Fabrizio, Balboni, Gianfranco, Salvadori, Severo, Sacerdote, Paola, Negri, Lu

Journal:

BioMed Research International

Year:

2015

Language:

english

File:

PDF, 11.07 MB

english, 2015

50

Osteogenic and Neurogenic Stem Cells in Their Own Place: Unraveling Differences and Similarities Between Niches

Lattanzi, Wanda, Parolisi, Roberta, Barba, Marta, Bonfanti, Luca

Journal:

Frontiers in Cellular Neuroscience

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015